Non-Win32 Malicious Files
There are heaps of Non-Win32 malicious file currently in the wild. These files are crafted to allow attackers to remotely execute arbitrary code. Although, it exploits known vulnerabilities, but still attackers find it useful as most of us do not bother applying security updates. So, the effect is massive installation of various threats in your computer.
Solution: Flash Player Update
FileType: RIFF Windows Animated Cursor
Solution: Microsoft Security Bulletin MS07-017
Solution: Adobe Reader and Acrobat Security Update
Solution: Update to latest version (version 3.61 and onwards)
Other non-exploited files:
FileType: DOC, Excel, PPT, JPEG, CHM
Behaviour: Drops and Install malicious EXE file
Filetype: ASF (Windows Audio/Video Files)
Behaviour: Connects to remote IP address to download malicious EXE file
For these kind of files, please make sure its coming from trusted source and make sure you have security software with updated signature installed.